Pharmaceutical Patents mainly revolve around molecules/ moieties which function as highly potent pharmaceutical drugs. These molecules/moieties are chemical structures which are claimed in patents mainly in the form of Markush claims.
A Markush claim or structure is one with multiple ‘functionally equivalent’ chemical entities allowed in one or more parts of the compound which implies that the alternative equivalent functional groups can also be a part of a chemical structure. The functionally equivalent chemical entities recited in a claim such as ”selected from the group A,B,C and D” are referred to as members of the the Markush group and belong to a recognized physical or chemical class. Such claims define wide spectrum of technical information.
For example, in the above structure, each of the “A1”,”A2”, “A3”, “A4”,”E” and “R” group in the formula given above can be selected from multiple different moieties and hence multiple structures can be formed from one particular Markush Structure.
Therefore, a comprehensive chemical structure search as well as analysis of such Markush structures require an amalgamation of IP expertise and thorough technical knowledge of chemical structures. Our teams at TT Consultants, fulfill these requirements and produce the best possible results by conducting extensive searches on a specialized database like STN (REGISTRY,MARPAT AND CAplus). Also, searches are performed on databases like PUBCHEM and SureChEMBL.
Moreover, each of our structure searches is backed by a rigorous in-depth keyword based search on several Paid and non-paid patent search databases. Besides keywords, these searches involve extensive class-based, assignee/inventor based search as well.
IP searches pertaining to biological sequences is focused on either nucleic acid sequences (DNA or RNA) or amino acid sequences (Proteins/Peptides). A plethora of existing patent as well as non-patent literature is on biological sequences and therefore this search type is of great significance to the emerging players in the field of IP.
The prime requirement for an extensive sequence search is the blend of the fundamental knowledge of bio-informatics tools such as sequence alignment and the skills to perform smart searching on various sequence databases. At TT Consultants, our team, well-versed with both nucleotide and protein sequences conducts an exhaustive search using various tools and databases like NCBI-BLAST, UNIPROT, Expasy, EMBL, RSCB-PDB and Patent Lens. Also, searches are conducted on paid databases like PCTgene and Dgene on special request.
Moreover, like our structure searches, each of our sequence searches is backed by a rigorous in-depth keyword based search on several Paid and non-paid patent search databases. Besides keywords, these searches involve extensive class-based, assignee/inventor based search as well.